Ipilumumab Plus Pembrolizumab Vs Pembrolizumab Alone In PdL1 More Than 50 Percentage Which Is Better
12 Mar, 2021
Dr. Rajesh Bollam
#Lungcancer
#is more always better ?
Ipilumumab plus pembrolizumab vs pembrolizumab alone in pdL1 more than 50 percentage
Which is better
Single agent pembrolizumab is better
The addition of IPI in #lungCancer failed AGAIN to improve survival combined w/ another ICI (here Pembro)
NO OS & PFS benefit (HR>1)
High % of irAEs (20.2 vs 7.8%)
Mono ICI remains t standard in PDL1≥50%
full JCO just out
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